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  • Title: Preliminary experience with the use of self-expanding stent as a thrombectomy device in ischemic stroke.
    Author: Cohen JE, Gomori JM, Leker RR, Eichel R, Arkadir D, Itshayek E.
    Journal: Neurol Res; 2011 May; 33(4):439-43. PubMed ID: 21535945.
    Abstract:
    OBJECTIVES: Stent-based techniques may allow rapid arterial recanalization in acute stroke. We present our experience using a self-expanding stent to achieve transient bypass, and then as a thrombectomy device, with no permanent stent implantation, in acute stroke. MATERIAL AND METHODS: Six patients (mean age 55, range 35-71) presented with major ischemic stroke secondary to large vessel occlusion. Patients had a National Institutes of Health stroke scale score >17, no intracerebral hemorrhage or early infarction, and a poor collateral supply to the affected parenchyma. Within 6 hours of symptom onset, a stent (Solitaire; ev3 Inc., Irvine, CA, USA) was deployed across the entire occluded segment. Repeat angiogram was performed to evaluate the reconstituted flow. The balloon of the guide-catheter was inflated for proximal carotid occlusion. The partially deployed stent was slowly pulled back (mechanical thrombectomy step) under continuous aspiration. Suction was repeated to ensure the aspiration of any clot remnants. RESULTS: In all the cases, complete recanalization (Thrombolysis in Myocardial Infarction revascularization and reperfusion score of 3) was achieved in less than 60 minutes after femoral access, and a single thrombectomy attempt was sufficient to achieve clot removal. No stent was permanently implanted. Modified Rankin scores were 0-2 in all patients at a mean follow-up of 1 month. CONCLUSIONS: The presented approach allowed three desired effects: rapid endovascular revascularization, clot removal, and no need of leaving a permanent implant. In our preliminary experience this simple and rapid stent-based mechanical thrombectomy technique has had an unprecedented success rate.
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