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Title: Probing β-(1→3)-D-glucans interactions with recombinant human receptors using high-resolution NMR studies. Author: Sylla B, Guégan JP, Wieruszeski JM, Nugier-Chauvin C, Legentil L, Daniellou R, Ferrières V. Journal: Carbohydr Res; 2011 Sep 06; 346(12):1490-4. PubMed ID: 21546004. Abstract: A full characterization of the high-resolution NMR spectrum of the laminarihexaose is described and used for the determination of the binding epitope of the more complex but structurally related laminarin. These biophysical data extend the current knowledge of β-glucans/Dectin-1 interactions and suggest different biological mechanisms in close relation with the size of the saccharidic chain.[Abstract] [Full Text] [Related] [New Search]