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  • Title: Paraganglioma mimicking a pancreatic neoplasm.
    Author: Lightfoot N, Santos P, Nikfarjam M.
    Journal: JOP; 2011 May 06; 12(3):259-61. PubMed ID: 21546704.
    Abstract:
    CONTEXT: Paragangliomas are rare tumours of neural crest origin. Extra-adrenal pancreatic paragangliomas are exceptionally rare. CASE REPORT: A 66-year-old man with abdominal pain was noted to have a complex pancreatic head and uncinate process mass on imaging. He underwent complete resection by pancreaticoduodenectomy with final pathology confirming a 6 cm paraganglioma without evidence of metastases. On histology the tumour was arising from the retroperitoneum and abutting the pancreas. The patient was disease free at 14-month follow-up. CONCLUSION: Pancreatic paragangliomas represent in many cases the retroperitoneal extension of a paraganglioma into the pancreas rather than a true pancreatic neoplasm. Although generally benign, the risk of malignant transformation justifies aggressive management.
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