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  • Title: Detection and typing of human papillomavirus DNA from cervical biopsies by the slot-blot hybridization method.
    Author: David F, Levy R, Lucotte G.
    Journal: Mol Cell Probes; 1990 Feb; 4(1):53-61. PubMed ID: 2156157.
    Abstract:
    Cervical biopsies collected from 105 consecutive patients participating in a prospective follow-up study for cervical human papillomavirus (HPV) infections were tested for the presence of HPV 6, 11, 16 and 18 DNA by the slot-blot hybridization method. Detectable HPV types 6 and 11 could be distinguished in high stringency hybridization assay. The overall HPV-DNA detection rate was 35.2% in our group of patients. The slot-blot technique is more rapid than Southern-blotting procedure and well suited for analysis of multiple specimens.
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