These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [POEMS syndrome diagnosed by detection of M-protein on immunofixation and increased level of vascular endothelial growth factor].
    Author: Hattori Y, Taguchi J, Imai N, Wasano K, Matsuura S, Koharazawa H, Ishigatsubo Y, Fujisawa S.
    Journal: Rinsho Ketsueki; 2011 Apr; 52(4):219-22. PubMed ID: 21566409.
    Abstract:
    A 48-year-old male with Castleman disease developed symptoms typical of POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal-protein and skin changes) but M-protein was not detected by immunoelec-trophoresis. He was diagnosed as having POEMS syndrome based on IgA-λ detected by immunofixation electrophoresis and an increased level (3,170 pg/ml) of vascular endothelial growth factor (VEGF). After diagnosis, the patient underwent autologous peripheral blood stem cell transplantation safely and remained relapse-free and in good condition for 15 months. This case suggests that immunofixation electrophoresis and detection of elevated serum VEGF level are useful methods for earlier diagnosis of POEMS syndrome.
    [Abstract] [Full Text] [Related] [New Search]