These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [The mutagenic action of the dust of natural zeolites and chrysotile asbestos].
    Author: Durnev AD, Suslova TB, Cheremisina ZP, Dubovskaia OIu, Nigarova EA, Korkina LG, Seredenin SB, Velichkovskiĭ BT.
    Journal: Eksp Onkol; 1990; 12(2):21-4. PubMed ID: 2156664.
    Abstract:
    The cell chemiluminescence method was used to demonstrate the ability of asbest and zeolite dusts from 8 deposits of the USSR to induce generation of free oxygen radicals in the phagocytosing cells suspension. It has been found that asbest and zeolite (0.01 and 0.05 mg/ml) increase levels of cells with chromosome aberrations in human cell cultures. The cytogenetic effect of asbest was inhibited by superoxide dismutase (50 mg/ml). The damaging effect of zeolite was decreased by the pharmacological drug bemithyl (0.007-0.07 mM) and completely eliminated by catalase (20 mg/ml). The results obtained indicate that mutagenic effect of dust particles of asbest and zeolite is mediated by oxygen radicals.
    [Abstract] [Full Text] [Related] [New Search]