These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Sparing of visual field perception in neonatal but not adult cerebral hemispherectomized cats. Relationship with oxidative metabolism of the superior colliculus.
    Author: Hovda DA, Villablanca JR.
    Journal: Behav Brain Res; 1990 Mar 05; 37(2):119-32. PubMed ID: 2157459.
    Abstract:
    Following cerebral hemispherectomy and using a lick-suppression test, adult-lesioned cats showed a complete contralateral hemianopsia, while neonatal-lesioned animals reliably responded to stimuli presented out to 45 degrees in the visual field contralateral to the lesion. In adult-lesioned cats oxidative metabolism of the superior colliculus ipsilateral to the hemispherectomy was markedly depressed as compared to the contralateral colliculus. In contrast, in the neonatal-lesioned cats this metabolic imbalance was mild. We propose that this ipsilateral depression of oxidative metabolism reflects the loss of excitatory corticotectal input which has been postulated as being partly responsible for the hemianopsia following a unilateral visual cortex ablation. Here we demonstrate, in addition, that this phenomenon is affected by developmental factors and suggest that differential age-at-lesion anatomical effects may also be involved.
    [Abstract] [Full Text] [Related] [New Search]