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  • Title: [In vitro models for the analysis of inflammatory processes in sarcoidosis].
    Author: Strausz J, Müller-Quernheim J.
    Journal: Pneumologie; 1990 Mar; 44(3):694-8. PubMed ID: 2158089.
    Abstract:
    Currently there are no animal models available for interstitial lung diseases with unknown origin, such as sarcoidosis. Inflammatory cells obtained from patients have several disadvantages for the in-vitro verification of pathogenetical concepts. Thus, in-vitro models are desirable. Employing cell lines we present models that are suited to study the angiotensin-converting enzyme release and the production of oxygen radicals by activated macrophages and their fusion to giant cells.
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