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  • Title: Citronellol and geraniol, components of rose oil, activate peroxisome proliferator-activated receptor α and γ and suppress cyclooxygenase-2 expression.
    Author: Katsukawa M, Nakata R, Koeji S, Hori K, Takahashi S, Inoue H.
    Journal: Biosci Biotechnol Biochem; 2011; 75(5):1010-2. PubMed ID: 21597168.
    Abstract:
    We evaluated the effects of rose oil on the peroxisome proliferator-activated receptor (PPAR) and cyclooxygenase-2 (COX-2). Citronellol and geraniol, the major components of rose oil, activated PPARα and γ, and suppressed LPS-induced COX-2 expression in cell culture assays, although the PPARγ-dependent suppression of COX-2 promoter activity was evident only with citronellol, indicating that citronellol and geraniol were the active components of rose oil.
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