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Title: Resolution of cytochrome oxidase into two component complexes. Author: Fry M, Vande Zande H, Green DE. Journal: Proc Natl Acad Sci U S A; 1978 Dec; 75(12):5908-11. PubMed ID: 216000. Abstract: Cytochrome c oxidase (ferrocytochrome c: oxygen oxidoreductase, EC 1.9.3.1) has been resolved into a pair of complexes of unequal molecular weight. The larger complex (electron transfer complex) contains exclusively the oxidation-reduction proteins characteristic of cytochrome oxidase; the smaller complex (ion transfer complex) shows exclusively the capability for cation-dependent induction of the fluorescence of 8-anilino-1-naphthalenesulfonic acid--a capability demonstrable in preparations of cytochrome oxidase. The duplex nature of cytochrome oxidase has important implications for the mechanism of energy coupling.[Abstract] [Full Text] [Related] [New Search]