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  • Title: [Chronic, fatal, neonatally-acquired cytomegalovirus disease with hypereosinophilia and multiple organ involvement].
    Author: Ramelli GP, Gebbers JO, Tönz O.
    Journal: Schweiz Med Wochenschr; 1990 Apr 28; 120(17):632-40. PubMed ID: 2160124.
    Abstract:
    The case is reported of a boy who died at age four from perinatally acquired persistent cytomegalovirus (CMV) infection associated with hypereosinophilia. Although no primary immunodeficiency was found he developed chronic CMV infection of the lungs, liver, bones, kidneys and finally brain. The clinical picture was dominated for a long period by asthmatic attacks due to severe obstructive bronchopulmonary disease. The possible immunological background to CMV infection and the clinical significance of the associated hypereosinophilia are discussed.
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