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  • Title: Functional FCGR2B gene variants influence intravenous immunoglobulin response in patients with Kawasaki disease.
    Author: Shrestha S, Wiener HW, Olson AK, Edberg JC, Bowles NE, Patel H, Portman MA.
    Journal: J Allergy Clin Immunol; 2011 Sep; 128(3):677-80. PubMed ID: 21601260.
    Abstract:
    In Kawasaki Disease patients, the authors show associations between high-dose intravenous immunoglobulin (IVIG) response and a polymorphism in the FCγRIIB. This provides basis for defining the IVIG regulatory mechanisms and pharmacogenomic approach to IVIG therapy.
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