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  • Title: [Surgical management of sinonasal and adjacent skull base benign fibro-osseous lesions].
    Author: Guo J, Zhang W, Yin S, Guan J.
    Journal: Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2011 Mar; 25(5):226-31. PubMed ID: 21604470.
    Abstract:
    OBJECTIVE: To explore the use of transnasal endoscopy and open surgical approaches for management of sinonasal and adjacent skull base benign fibro-osseous lesions, the surgical methods, precautions, clinical efficacies were also described. METHOD: Fifteen patients were reviewed, including osteoma in 6 cases, Ossifying fibroma in 2 cases and fibrous dysplasia in 7 cases. Analyzed the pathological features and CT images, and to select surgical approach according to the location and extent of lesions. Eleven patients were operated through transnasal endoscopic procedure, including 7 cases with ipsilateral nasal approach and 4 cases with extended binasal approach; 4 cases with open surgical approach, including trans-eyebrow approach in 1 case and bicoronal approach in 3 cases. RESULT: All patients were followed up for 2 months to 4 years, gross resection of lesions in 10 cases but partial resection in 5 cases with fibrous dysplasia. The clinical symptoms and facial deformity in all cases were eliminated or significantly relieved postoperatively. Cerebrospinal fluid leakage occurred in 1 case, was successfully repaired during the endoscopic operation. Preoperative diplopia in 3 cases, 2 cases disappeared after six months, one case was improved significantly. There were no postoperative orbital or intracranial complications. CONCLUSION: Surgery is an effective means to resect lesions which had obviously clinical symptoms. The location and extent of lesions were the decisive factor to choose an open or endoscopic approach. Endoscopic sinus surgery can manage the midline skull base lesions which extend from the posterior wall of the frontal sinus to the clivus, well the open surgical approach is suitable for lesions locating the area beyond the medial orbital wall. No matter choosing which approach, osteoma, ossifying fibroma can be completely removed. For the fibrous dysplasia, as an extensive but self-limiting lesion, the surgery is performed only for relieving symptoms and facial deformity. So the partial resection is preferred and reasonable other than radical total resection. Even the severe fibrous dysplasia lesions caused the optic canal stenosis but present normal vision, it is unnecessary to perform prophylactic decompression of the optic nerve.
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