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  • Title: Oxytocin versus dinoprostone vaginal insert for induction of labor after previous cesarean section: a retrospective comparative study.
    Author: Gómez LR, Burgos J, Cobos P, Melchor JC, Osuna C, Centeno Mdel M, Larrieta R, Fernández-Llebrez L, Martínez-Astorquiza T.
    Journal: J Perinat Med; 2011 Jul; 39(4):397-402. PubMed ID: 21604996.
    Abstract:
    OBJECTIVE: To compare the efficacy and safety of two methods for induction of labor after previous cesarean section. METHODS: To compare 247 women with a previous cesarean section who were induced with a dinoprostone vaginal insert and 279 women with a previous cesarean section induced with oxytocin, between 2001 and 2008. We evaluated vaginal delivery rate, maternal morbidity and newborn morbidity and mortality. RESULTS: The overall rate of vaginal delivery was 65.2%. We did not find significant differences between induction with dinoprostone vaginal insert and oxytocin in the rate of cesarean section performed (35.6% vs. 34.1%, P=0.71). There were nine cases of uterine rupture (rate of 1.7%), of which four occurred with dinoprostone vaginal insert and five when using oxytocin (P=0.89). We found no significant differences in neonatal outcomes. CONCLUSIONS: Both tested methods appear to be equally safe and effective for induction of labor in women with a previous cesarean section.
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