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  • Title: D-penicillamine induced pemphigus treated with methylprednisolone pulse therapy.
    Author: Wouters EA, De Clerck LS, Francx L, Stevens WJ.
    Journal: Acta Clin Belg; 1990; 45(1):15-9. PubMed ID: 2161600.
    Abstract:
    A patient with severe rheumatoid arthritis received d-penicillamine treatment for 16 months. She developed mild pruritus 6 months after d-penicillamine initiation, and severe pemphigus 10 months after d-penicillamine was changed to azathioprine. Subsequent methylprednisolone pulse therapy resulted in a transient clinical remission of pemphigus. A literature review of d-penicillamine induced pemphigus and high dose methylprednisolone pulse therapy is presented.
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