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  • Title: Mature cystic teratoma with malignant transformation to adenocarcinoma.
    Author: Muramatsu T, Nishii T, Ohmori K, Shiono M.
    Journal: Ann Thorac Surg; 2011 Jun; 91(6):1971-3. PubMed ID: 21619995.
    Abstract:
    An anterior mediastinal tumor had been found in a 65-year-old woman 10 years previously, and she had been followed-up under the diagnosis of a mature cystic teratoma. Changes in the structure of the inside of the mediastinal cystic tumor were observed on a chest computed tomography image, and she was referred to our hospital for surgical intervention. The tumor was removed and was determined to be a mature teratoma. An adenocarcinoma was also observed in part of this cystic lesion. From these findings, the lesion was diagnosed as a malignant change in a mediastinal mature teratoma. Because few if any changes tend to be observed in the cystic wall of such cases, an aggressive resection of such mature cystic teratomas is therefore recommended.
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