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  • Title: Semen and hormonal parameters in men with chronic hepatitis C infection.
    Author: Hofny ER, Ali ME, Taha EA, Nafeh HM, Sayed DS, Abdel-Azeem HG, Abdou EF, Kamal GM, Mostafa T.
    Journal: Fertil Steril; 2011 Jun 30; 95(8):2557-9. PubMed ID: 21620397.
    Abstract:
    Male patients with chronic hepatitis C virus (HCV) infection (n = 57) demonstrated a statistically significant decrease in semen volume, sperm count, and progressive sperm motility and a statistically significant increase in abnormal sperm morphology compared with healthy controls (n = 40). The duration of the HCV infection was negatively correlated with semen volume and sperm motility where the HCV RNA viral load was negatively correlated with sperm count and sperm motility. Chronic HCV patients had statistically significantly lower total serum testosterone and higher serum E(2) and prolactin levels compared with healthy controls.
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