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  • Title: [Cultivation of hepatitis A virus in various cell lines and isolation of DNA sequences].
    Author: Farashian VR, Bychenko AB, Kuzaeva IA, Artemov EK, Khizhniakova TM, Zhdanov VM.
    Journal: Vopr Virusol; 1990; 35(1):23-6. PubMed ID: 2163567.
    Abstract:
    Using the MBB/11/5 strain originally adapted to the PLC/PRF/5 cell line, reproduction of the virus in diploid cells of human embryo fibroblasts, continuous primate lines (RAMT, FRhK-4) and human urinary bladder tumor (T-24) lines was studied. We obtained HAV DNA sequences (about 99% from vRNA) for the MBB/11/5 strain which were used as a probe for demonstration of vRNA synthesis in the infected cells.
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