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  • Title: Primary bilateral adrenal lymphoma revealed by hemophagocytic syndrome.
    Author: Alaoua A, Gilbert G, Ghannouchi N, Houchlef M, Letaief A, Bahri F.
    Journal: Ann Endocrinol (Paris); 2011 Jun; 72(3):247-50. PubMed ID: 21640976.
    Abstract:
    Primary adrenal lymphoma is rare. It is often bilateral and in most of the cases of B-cell type. The clinical features are various and not specific. We report a case of a 69-year-old woman who had a diffuse large B-cell lymphoma associated with hemophagocytic syndrome. The abdominal imaging reveals the existence of bilateral adrenal hypertrophy. A CT scan-guided biopsy concluded to a diffuse large B-cell lymphoma CD 20-positive associated EBV. The treatment consisted on "CHOP like" chemotherapy associated with rituximab. Primary adrenal lymphoma has a poor prognosis, even more poorly if associated with hemophagocytic syndrome.
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