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  • Title: Efficient synthesis, structural characterization and anti-microbial activity of chiral aryl boronate esters of 1,2-O-isopropylidene-α-D-xylofuranose.
    Author: Trivedi R, Rami Reddy E, Kiran Kumar Ch, Sridhar B, Pranay Kumar K, Srinivasa Rao M.
    Journal: Bioorg Med Chem Lett; 2011 Jul 01; 21(13):3890-3. PubMed ID: 21641208.
    Abstract:
    A simple and efficient synthetic approach toward a series of chiral aryl boronate esters, starting from D-xylose, as anti-microbial agents, is described herein. Minimum inhibitory concentration and zone of inhibition revealed that these derivatives exhibit potent anti-bacterial and anti-fungal properties. Herein, we report the first anti-microbial activity of this class of compounds. All products have been characterized by NMR ((1)H, (13)C and (11)B), IR, elemental and mass spectral study.
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