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  • Title: Synthesis and screening of (E)-1-(β-D-galactopyranosyl)-4-(aryl)but-3-ene-2-one against Mycobacterium tuberculosis.
    Author: Mugunthan G, Ramakrishna K, Sriram D, Yogeeswari P, Ravindranathan Kartha KP.
    Journal: Bioorg Med Chem Lett; 2011 Jul 01; 21(13):3947-50. PubMed ID: 21641797.
    Abstract:
    A series of galactose-derived aryl enones were synthesised and screened against Mycobacterium tuberculosis H(37)Rv. Preliminary results were promising with MIC values in the range 1.56-12.5 μg/mL.
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