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  • Title: Stereoselective aza-Darzens reactions of tert-butanesulfinimines: convenient access to chiral aziridines.
    Author: Solá TM, Churcher I, Lewis W, Stockman RA.
    Journal: Org Biomol Chem; 2011 Jul 21; 9(14):5034-5. PubMed ID: 21643589.
    Abstract:
    Stereoselective synthesis of 2,3-di- and 2,2',3-tri-substituted aziridines in good yields and excellent diastereoselectivities are achieved through aza-Darzens reactions of a range of tert-butanesulfinyl aldimines and ketimines with ethyl bromoacetate.
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