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  • Title: Synthesis of P-triazinylphosphonium salts--hybrid molecules with potential antimicrobial activity.
    Author: Kolesińska B, Motylski R, Kamiński ZJ, Kwinkowski M, Kaca W.
    Journal: Acta Pol Pharm; 2011; 68(3):387-91. PubMed ID: 21648193.
    Abstract:
    The new hybrid drugs combining in a single molecule triazine ring attached to phosphonium salt were prepared and their bactericidal activity against Gram-positive bacteria Staphylococcus aureus ATCC43300 (MRSA - methycyline resistant Staphylococcus aureus strain) two Gram-negative bacteria Escherichia coli CCUG31997 serotype O153 (EPEC - enteropathogenic Escherichia coli strain), Proteus mirabilis 1784 (MDR - multidrug resistant clinical strain) were determined using microdilution method.
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