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  • Title: Prospective comparison of biopsy results from curettage and hysteroscopy in postmenopausal uterine bleeding.
    Author: Lee DO, Jung MH, Kim HY.
    Journal: J Obstet Gynaecol Res; 2011 Oct; 37(10):1423-6. PubMed ID: 21651668.
    Abstract:
    AIM: To evaluate the diagnostic accuracy of biopsy by dilatation and curettage in postmenopausal women with abnormal uterine bleeding. MATERIAL AND METHODS: A prospective observational study conducted with 112 consecutive postmenopausal women. Biopsy by dilatation and curettage was immediately followed by hysteroscopic biopsy and the histologic results were compared. RESULTS: By curettage, although performed under anesthesia, 3/3 (100%) cases of endometrial hyperplasia were reported as normal proliferative endometrium. There were two endometrial cancers (1.8%) and one case was missed as normal endometrium by curettage. Among endometrial polyps, only 3/39 (7.7%) cases were diagnosed by curettage. CONCLUSIONS: In postmenopausal women with abnormal uterine bleeding, biopsy by curettage may be not reliable for evaluation of endometrial pathology.
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