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  • Title: Evaluation of a new polysulfone hemofilter for continuous renal replacement therapy.
    Author: Floris M, Marchionna N, Clementi A, Kim JC, Cruz DN, Nalesso F, Zanella M, Garzotto F, de Cal M, Virzì GM, Brendolan A, Ronco C.
    Journal: Blood Purif; 2011; 32(2):133-8. PubMed ID: 21654165.
    Abstract:
    New strategies using continuous renal replacement therapy as a tool to achieve immunomodulation in septic acute kidney injury have been proposed. The hypothesis is based on the possibility to remove inflammatory mediators and oxidants in a wide spectrum of molecular weights, thanks to new, highly permeable synthetic membranes. A new polysulfone hemofilter with high permeability and a sharp high cut-off membrane (CUREFLO™; Asahi Kasei Kuraray Medical Co., Ltd., Tokyo, Japan) has been evaluated in this study to assess IL-6 and advanced oxidation protein product removal in critically ill patients undergoing continuous renal replacement therapy. Unit performance, sieving coefficients and clearances were evaluated in fourteen patients undergoing continuous veno-venous hemofiltration and continuous veno-venous hemodialysis.
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