These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Two-ply biodegradable nerve guide: basic aspects of design, construction and biological performance.
    Author: Hoppen HJ, Leenslag JW, Pennings AJ, van der Lei B, Robinson PH.
    Journal: Biomaterials; 1990 May; 11(4):286-90. PubMed ID: 2166595.
    Abstract:
    A synthetic biodegradable nerve guide was constructed of two polymeric layers: an inner microporous layer prepared from a copolymer of L-lactide and epsilon-caprolactone (pore size range 0.5-1 micron) and an outer microporous layer prepared from a polyurethane/poly(L-lactide) mixture (pore size range 30-70 microns). This nerve guide was used to bridge a 7 mm gap in the right sciatic nerve of rats. It enabled the sciatic nerve to regenerate across the gap, forming a new, well-defined nerve that effectively re-established the contact between the proximial and distal nerve end, as effective as an autograft.
    [Abstract] [Full Text] [Related] [New Search]