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  • Title: Malignant jugulotympanic paraganglioma.
    Author: Johnstone PA, Foss RD, Desilets DJ.
    Journal: Arch Pathol Lab Med; 1990 Sep; 114(9):976-9. PubMed ID: 2167653.
    Abstract:
    Jugulotympanic paragangliomas are neoplasms that arise in the jugular bulb (glomus jugulare tumor) or temporal bone (glomus tympanicum tumor). They are histologically similar to carotid body tumors; both are derived from extra-adrenal paraganglia. Of only 20 metastases reported, five had biopsy-proved bone involvement. We present a review of the literature of metastatic jugulotympanic paragangliomas and report a case that recurred locally with regional metastases 10 years after initial presentation and metastasized to spine 13 years later. Histologic data are reviewed, and potential treatment regimens are contrasted.
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