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  • Title: Protein synthesis: Stop the nonsense.
    Author: Ferré-D'Amaré AR.
    Journal: Nature; 2011 Jun 15; 474(7351):289-90. PubMed ID: 21677740.
    Abstract:
    The amino acid sequence of proteins is specified by trinucleotides (codons), and their ends by one of three stop codons. A new study reveals how a subtle biochemical alteration can reprogram stop codons into amino acid-encoding codons at the messenger RNA (mRNA) level, without altering the DNA from which the mRNA is transcribed.
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