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  • Title: [Gadolinium-DTPA as an oral contrast medium for MR tomography of the abdomen].
    Author: Krahe T, Dölken W, Lackner K, Houselog M, Habscheid W, Clauss W.
    Journal: Rofo; 1990 Aug; 153(2):167-73. PubMed ID: 2168072.
    Abstract:
    150 MR examinations of the upper abdomen were carried out after the oral administration of 5 ml/kg body weight of a gadolinium DTPA formulation (1.0 mmol/l, 15 g/l mannitol), with reference to the delineation of the pancrease, the liver and intra-abdominal fat. For comparison, 100 MR examinations without oral opacification of the G.I. tract were evaluated. Contrast administration resulted in a signal-intensive demonstration of the G.I. tract for all measurement sequences. The intraluminal contrast improved the distinction between normal and abnormal structures. T1 and T2 sequences and the demonstration of fat on T2-weighted series. T1-weighted series showed the best diagnostic results. In 25% there was meteorism and diarrhoea within 24 hours of the administration of the oral contrast.
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