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  • Title: [Stromal tumors of jejunum and ileum].
    Author: Ciobotaru O, Ciobotaru OR, Dragomir C.
    Journal: Rev Med Chir Soc Med Nat Iasi; 2011; 115(1):111-5. PubMed ID: 21688567.
    Abstract:
    UNLABELLED: Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract and 25% are in the small intestine. MATERIAL AND METHOD: A retrospective study was performed on 73 patients diagnosed with intestinal cancer in three hospitals in Iasi and Galati, in a period of 12 years (1998-2009). RESULTS: Stromal tumors represents 11.5% of malignant tumors of jejunum and ileum, and the average age of diagnosis was 55 years; male to female incidence was 1 : 2 (chi2 = 0.66, p > 0.05). 66.66% of patients came from urban areas (chi2 = 0.66, p > 0.05). The most frequent signs and symptoms were abdominal meteorism and abdominal pain (83%). There were no correlations between admission and discharge diagnosis. CD117 was present in all patients; CD34 was present in 66.66% of them. Survival at 2 years was 66.67% and at 5 years was 33.33%. CONCLUSIONS: Preoperative diagnosis is often difficult to make, many patients come to doctors in advanced-stage and the five-year survival rate is slow. The most frequent tumor markers were CD117 and CD34.
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