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  • Title: [Clinical significance of glycosylated serum protein in patients with diabetic nephropathy].
    Author: Li PL, Yang R, Zhou Y, Chen H, Cai DH.
    Journal: Nan Fang Yi Ke Da Xue Xue Bao; 2011 Jun; 31(6):1093-4. PubMed ID: 21690078.
    Abstract:
    OBJECTIVE: To explore the relations between fasting blood glucose (FBG), glycosylated hemoglobin A1c (HbA1c) and glycosylated serum protein (GSP). METHODS: FBG, HbA1c and GSP were measured in 303 patients with diabetic nephropathy and in 167 non-diabetic patients with comparable baseline data, and the correlations between FBG, HbA1c and GSP were analyzed. RESULTS: GSP levels were significantly higher in patients with diabetic nephropathy than in the non-diabetic patients (P<0.01). In patients with diabetic nephropathy, GSP levels were found to positively correlate to FBG (r=0.606) and HbA1c (r=0.733). CONCLUSION: Patients with diabetic nephropathy show strong correlations between FBG, HbA1c and GSP. GSP detection is convenient, stable, and practical in evaluating the average FBG over a short term, which reduces the interference by FBG fluctuations in conventional blood glucose monitoring.
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