These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [The effect of the selective blocking of synaptic transmission in the parafascicular complex on the neuronal activity of the sensorimotor cortex].
    Author: Kruchenko ZhA, Sachenko VV.
    Journal: Neirofiziologiia; 1990; 22(3):327-36. PubMed ID: 2169030.
    Abstract:
    Peculiarities of spike responses of the sensorimotor cortex neurons and conditional activity induced by blockade of noradrenergic and serotoninergic inputs of the PF complex (CM-PF) have been studied in chronic experiments on cats with a preliminarily conditioned placing reaction to an auditory stimulus--a click. It is shown that an increase in the background activity of neurons of the sensorimotor cortex was caused by microinjections of obsidan, an adrenergic blocker, while depression--by microinjections of lysergoamid, a serotonin blocker. The effect of both blockers on the neuronal reactions evoked by conditional auditory stimulus was the same (depression). Both conditional placing and unconditional one were removed by partial blockade of monoaminergic inputs for 30-60 min. A conclusion is made that the character of the influence of the monoaminergic system on the sensorimotor cortex is determined not only by direct, but also by indirect influences due to neurons of the CM-PF complex of thalamic nuclei.
    [Abstract] [Full Text] [Related] [New Search]