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  • Title: Weight-based loading of vancomycin in patients on hemodialysis.
    Author: Brown M, Polisetty R, Gracely EJ, Cuhaci B, Schlecht HP.
    Journal: Clin Infect Dis; 2011 Jul 15; 53(2):164-6. PubMed ID: 21690623.
    Abstract:
    We evaluated weight-based loading doses of vancomycin and resulting initial prehemodialysis concentrations. Modeling demonstrated modest correlation between dose administered, age, and initial concentration achieved. Actual body weight-based loading of vancomycin predictably achieves therapeutic initial concentrations in patients who receive hemodialysis.
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