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  • Title: Inhibition by tetrandrine of calcium currents at mouse motor nerve endings.
    Author: Wiegand H, Meis S, Gotzsch U.
    Journal: Brain Res; 1990 Jul 30; 524(1):112-8. PubMed ID: 2169326.
    Abstract:
    The inhibition by the bis-benzyl-isoquinoline alkaloid tetrandrine of motor terminal calcium currents has been studied using extracellular, perineuronal electrodes in the M. triangularis preparation of the mouse. The calcium plateau current was irreversibly blocked, whereas the fast calcium current remained unaffected. From these results a calcium antagonism on neuronal calcium channels involved in transmitter release at motor nerve terminals is suggested.
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