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  • Title: REM sleep deprivation and pain thresholds in rats.
    Author: Hicks RA, Moore JD, Findley P, Hirshfield C, Humphrey V.
    Journal: Percept Mot Skills; 1978 Dec; 47(3 Pt 1):848-50. PubMed ID: 216974.
    Abstract:
    The relationship between REM sleep deprivation and pain threshold was measured using 36 Sprague-Dawley female rats. Relative to that of the controls, a significant lowering of threshold to painful electrical stimulation was observed during each of the post-treatment tests, i.e., immediate, and after 3- and 24-hr. recovery periods, for the animals which had been REM deprived.
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