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  • Title: [Kidney lesions in a diphtheria catamnesis].
    Author: Turovets EV, Zriachkin NI.
    Journal: Lik Sprava; 2010; (7-8):44-53. PubMed ID: 21714286.
    Abstract:
    150 persons aged from 16 to 65 years found in a diphtheria catamnesis have been observed. Clinical and laboratory as well as ultrasonic signs of kidney lesions in an acute period of a pharynx diphtheria have been studied. These signs corresponded to tubulo-interstitial nephritis. Obtained data testifies that more severe old form of diphtheria in the acute period is more often symptoms of kidneys lesion in a catamnesis period are revealed and they remain throughout long time. 47.5% of patients in a diphtheria catamnesis had clinical-laboratory and echographic signs of kidneys lesion, 81.3% of them clinically presented pain and edematic syndromes, uropoiesis and urine passage disturbances; depression of renal functions (concentration and depurination), an urinary syndrome; sonographic signs of kidneys lesion were observed and manifested at maximum level 1-3 years after an acute period of a pharynx diphtheria. Perimedullary thickness was revealed in 20-45% of patients depending on severity of the disease, it was combined with single and multiple calcifications and a calcification of pyramids papillas. According to ultrasonic data, the nephrocalcinosis has been found 1.2 times oftener after average degree of severity and 2 times oftener after severe degree of severity of pharynx diphtheria in comparison with mild form of the disease. The calcification of papillas of the pyramids, found out in a diphtheria catamnesis, had been developed in a place of necrosis of papillas of pyramids in patients in an acute period of disease.
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