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  • Title: [Effects of serotonin on antigen-nonspecific suppressors of the thymus].
    Author: Morozova NB.
    Journal: Biull Eksp Biol Med; 1990 Jul; 110(7):68-70. PubMed ID: 2171696.
    Abstract:
    Study of nonspecific suppressors of the thymus in inhibition of immune response by serotonin is carried out in CBA mice. We have tested a selective effect of 2-deoxyguanosine on antigen nonspecific T suppressors of the thymus. In syngeneic adoptive transfer on the 3rd day after immunization it is established that antigen nonspecific immune response (rosette-forming cells) after serotonin treatment amounts to 71%, in intact animals--37%. When estimating the plague forming cells the antigen nonspecific suppressive thymocytes make up 21.9% in immune mice, 62.5% in immune mice after serotonin treatment, 29.7% in intact animals.
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