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  • Title: Effects of chronic treatment with cadmium on ATPases, uptake of catecholamines, and lipid peroxidation in rat brain synaptosomes.
    Author: Rajanna B, Hobson M, Boykin M, Chetty CS.
    Journal: Ecotoxicol Environ Saf; 1990 Aug; 20(1):36-41. PubMed ID: 2171895.
    Abstract:
    The chronic effects of cadmium on specific activities of oligomycin-sensitive (OS) and -insensitive Mg2+ ATPase, Na(+)-K+ ATPase, lipid peroxidation, and uptake of catecholamines in brain synaptosomes of rats treated daily for 2 or 4 months were studied. Cadmium significantly decreased the specific activities of OS-Mg2+ ATPase, Na(+)-K+ ATPase, and uptake of [3H]-dopamine (3H-DA) and [3H]norepinephrine (3H-NE) and increased the lipid peroxidation.
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