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  • Title: [Radioembolization with (90)Y-labeled microspheres: post-therapeutic therapy validation with Bremsstrahlung-SPECT].
    Author: Grober OS, Nultsch M, Laatz K, Ulrich G, Seidensticker R, Pethe A, Dudeck O, Pech M, Knoop BO, Ricke J, Amthauer H, Geworski L.
    Journal: Z Med Phys; 2011 Dec; 21(4):274-80. PubMed ID: 21719264.
    Abstract:
    During the last years angiographic Selective Internal Radiotherapy (SIRT) with (90)Y-labelled microspheres has become a common technique for the local-ablative treatment of cancer patients. SIRT is a palliative therapy concept for the treatment of liver malignancies. As a result of (90)Y-decay as β(-)-emitter without a concomitant gamma radiation, Bremsstrahlung imaging is needed to validate the distribution achieved by radioembolisation. This article demonstrates the method of imaging through phantom measurement and shows the advantages of post-therapeutic tomography by means of a patient study. Approaches for further optimization of Bremsstrahlung imaging are discussed.
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