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  • Title: [Evaluation of stereometric parameters of optic disc and nerve fiber layer using HRT II. Report 3: measurement error of spectral-domain optical coherence tomography compared with Heidelberg retinal tomograph III].
    Author: Shpak AA, Malakhanova MK, Ogorodnikova SN.
    Journal: Vestn Oftalmol; 2011; 127(2):46-9. PubMed ID: 21721274.
    Abstract:
    The aim was to study reproducibility and variability of measurements of retinal nerve fiber layer (RNFL) using spectral-domain optical coherence tomography (SOCT) and to compare with error of Heidelberg retinal tomograph (HRT). 29 patients with initial primary open-angle glaucoma were examined using Heidelberg retinal tomograph III (HRT III) and SOCT (Cirrus HD-OCT). Intra- and interobserver errors (reproducibility and intraobserver variability coefficient) for mean RNFL thickness and its thickness in temporal, upper, nasal and inferior quadrants. Mean RNFL thickness measured with SD-OCT showed the highest intra- and interobserver reproducibility and minimal variability. Intraobserver variability coefficient was 3 times lower as compared with the best parameter measured with HRT (rim area) and it was 7 fold lower as compared with mean RNFL thickness measured with HRT. Thus study of RNFL using SD-OCT showed high reproducibility and low variability particularly for mean RNFL thickness. The measurement error of SOCT is lower as compared with HRT and provides the most accurate study of RNFL.
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