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  • Title: Effects of cytokines from virus-induced human lymphoblasts on the growth and viability of the promyelocytic leukemia cell line HL-60.
    Author: Sueishi S, Ando S, Yamauchi H, Oga J, Ootsuka Y, Nagano Y.
    Journal: J Interferon Res; 1990 Aug; 10(4):379-83. PubMed ID: 2172407.
    Abstract:
    Cells of the human B-cell lymphoblastic leukemia line, BALL-1, were stimulated with Sendai virus. It is shown that the crude culture supernatants contain not only interferon-alpha (IFN-alpha) and tumor necrosis factor-alpha (TNF-alpha) but also other cytokines, here collectively termed 'X' cytokines. The latter did not affect the cytostatic or differentiation-inducing effect of IFN-alpha but synergistically increased the cytotoxicity of TNF-alpha.
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