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  • Title: Identification of a new sildenafil analogue in a health supplement.
    Author: Ge X, Li L, Koh HL, Low MY.
    Journal: J Pharm Biomed Anal; 2011 Nov 01; 56(3):491-6. PubMed ID: 21726974.
    Abstract:
    A sildenafil analogue was detected and isolated from a health supplement claimed for human use. The structure of this new analogue was elucidated using LC-UV, LC-Orbitrap-MS, IR spectroscopy, 1D and 2D NMR. It was characterized as dithio-desmethylcarbodenafil containing 2 thiocarbonyl groups instead of 2 carbonyl groups, and 4-methyl substitution, on the piperazine ring, rather than 4-ethyl substitution, when compared to sildenafil.
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