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  • Title: In vitro evaluation of hexagonal polymeric micelles in macrophage phagocytosis.
    Author: Tsai HC, Chang CH, Chiu YC, Lin SY, Lin CP, Hsiue GH.
    Journal: Macromol Rapid Commun; 2011 Sep 15; 32(18):1442-6. PubMed ID: 21732463.
    Abstract:
    This paper develops a non-spherical polymeric micelle using an amphiphilic block copolymer and a porphyrin crystalline structure. The nanoscale polymer micelles were characterized by transmission electron microscopy (TEM) and atomic force microscopy (AFM), revealing particle sizes of approximately 150 nm with a particular shape in the hexagonal lattice. The shape shows the selective uptake efficacy for the HeLa and macrophage cells, and inhibits phagocytosis against the macrophage.
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