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  • Title: [Clinical study concerning of latamoxef concentration in the obstructed urinary tract].
    Author: Suzuki Y, Itoh S, Katoh M, Morita M, Fukushi Y, Toyota S, Katoh S, Oikawa K, Orikasa S, Majima K.
    Journal: Hinyokika Kiyo; 1990 Aug; 36(8):897-902. PubMed ID: 2173381.
    Abstract:
    Urinary LMOX concentration was studied in 18 patients with unilateral ureteral obstruction. The concentration of LMOX in the urine from the mild obstructed kidney was 124 to 2,140 micrograms/ml and 10 micrograms/ml in the severely obstructed ones. The difference was probably due to the intensity and the duration of the obstruction. The patient with 99mTc-DMSA renal uptake of less than 3% also had a urinary LMOX concentration of less than 7 micrograms/ml. The above results seem to show that 7 micrograms/ml in urinary LMOX concentration is a significant figure for treatment of UTI. 99mTc-DMSA renal uptake and renal echogram were used to estimate the excretion rate of antibiotics into the urine.
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