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  • Title: Superoxide anion radical induces lipid phase transitions that mimic temperature-induced phase-transition phenomenon of membrane lipids.
    Author: Kumar GP, Tillo N, Laloraya M, Nivsarkar M, Verma S, Singh A.
    Journal: Biochem Biophys Res Commun; 1990 Oct 30; 172(2):601-6. PubMed ID: 2173573.
    Abstract:
    A biological membrane is shown to undergo lipid-phase transition leading to increased membrane fluidity when exposed to extraneously generated superoxide anion radical. This phase-transition is several folds higher in magnitude when compared to the temperature-induced fluidity change at the transition temperatures. This finding could have significant importance since an altered membrane configuration may involve aspects of biochemistry, biophysics or physiology.
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