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  • Title: Signet-ring cell carcinoid of the gallbladder.
    Author: Papotti M, Galliano D, Monga G.
    Journal: Histopathology; 1990 Sep; 17(3):255-9. PubMed ID: 2173677.
    Abstract:
    A case of signet-ring cell carcinoid of the gallbladder is reported. The tumour diffusely infiltrated the gallbladder wall and extensively ulcerated the mucosa. Neoplastic nests were composed of numerous signet-ring cells mixed with clear endocrine cells. The latter expressed chromogranin A, gastrin and somatostatin and contained neurosecretory granules. The diagnostic problem of differentiating between signet-ring cell carcinomas and composite adenocarcinoma-carcinoid tumours is discussed.
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