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  • Title: [Successful chemotherapy of carcinomatosis of the bone marrow with disseminated intravascular coagulation from a rectal carcinoma found by eosinophilia].
    Author: Higashiyama A, Kudo M, Nagasako T, Kawamura N, Abiko S, Yamamoto Y, Takano M, Gotoh J, Tamaki T, Meguro J, Yonekawa M, Kawamura A, Tanino M.
    Journal: Nihon Shokakibyo Gakkai Zasshi; 2011 Jul; 108(7):1244-51. PubMed ID: 21737977.
    Abstract:
    A 71-year-old man with eosinophilia was given a diagnosis of poorly differentiated adenocarcinoma of the rectum. Further examination showed that it had invaded the bone marrow. He had disseminated intravascular coagulation (DIC) from disseminated carcinomatosis of the bone marrow after colostomy. Chemotherapy (mFOLFOX6) was successful and his eosinophil count, DIC score and tumor markers normalized. We were able to continue chemotherapy after 5 months from the outbreak of disseminated carcinomatosis of the bone marrow. It is said that disseminated carcinomatosis of the bone marrow has a poor prognosis, but we were able to obtain a good response in this case by chemotherapy.
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