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  • Title: Devastating intracardiac and aortic thrombosis: a case report of apparent catastrophic antiphospholipid syndrome during liver transplantation.
    Author: Gologorsky E, Andrews DM, Gologorsky A, Sampathi V, Sundararaman L, Govindaswamy R, Raveh Y, Tzakis AG, Pretto EA.
    Journal: J Clin Anesth; 2011 Aug; 23(5):398-402. PubMed ID: 21741809.
    Abstract:
    Fewer than 80 cases of intracardiac thrombosis and intraoperative pulmonary thromboembolism during liver transplantation have been described. We present a patient who suffered an intraoperative fulminant intracardiac and aortic thrombosis and posthumously was found to have had high anticardiolipin immunoglobulin M concentration and markers of hyperfibrinolysis in preoperatively collected plasma. Hemostatic therapy in the presence of circulating antiphospholipid antibodies and the pathogenesis of a catastrophic antiphospholipid syndrome are discussed.
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