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  • Title: The importance of congenital hypertrophy of the retinal pigment epithelium in familial adenomatous polyposis.
    Author: Martow J, Polomeno RC, Lewandowski R, Daly D, Miller S, Jutras L, Koehn D, Der Kaloustian VM.
    Journal: Can J Ophthalmol; 1990 Oct; 25(6):290-2. PubMed ID: 2174290.
    Abstract:
    We describe a family with familial adenomatous polyposis (FAP) and congenital hypertrophy of the retinal pigment epithelium (RPE). Three of five members with FAP showed flat, well-demarcated, round to oval pigmented patches of congenital hypertrophy of the RPE. We stress the importance of congenital hypertrophy of the RPE as a clinical marker in identifying patients with FAP since they are at risk for cancer.
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