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  • Title: Oral treatment with itraconazole of aspergilloma in cavitary lung cancer.
    Author: Impens N, De Greve J, De Beule K, Meysman M, De Beuckelaere S, Schandevyl W.
    Journal: Eur Respir J; 1990 Jul; 3(7):837-9. PubMed ID: 2175709.
    Abstract:
    We report a case of aspergilloma in a necrotic small cell lung cancer, where poor pulmonary function and performance status of the patient precluded surgical treatment. High dose Itraconazole, a new oral anti-mycotic drug, was given for 13 months. During this treatment there was a decrease of the fungus ball size and no haemoptysis. Moreover control of the aspergilloma allowed chemotherapeutic treatment of the underlying bronchocarcinoma.
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